Micronics' unique microFlow™ System is the first integrated microfluidics workstation with ultra-low-pulse twist syringe pumps. Micronics' twist syringe pumps allow flow rates of 1-10,000 nanoliters per second. These low-pulse pumps ensure reliable, reproducible and accurate results. The microFlow™ System comes complete with
- Programmable software - Windows based with Labview GUI
- MicroHydro™ Manifold - that fits the stage for most inverted microscopes for real-time analysis of fluids in flow
- Initial set of Active H™ or Active T™ Lab Cards
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The microFlow™ System has been shown to enable preparation of complex samples - including whole blood - for analysis or further chemical processing. The System is able to:
- Extract small molecular weight molecules and analytes (e.g., hormones and antibiotics) directly from whole blood and other particulate suspensions
- Function in < 5 minutes
- Operate easily on sample volumes from 5 to 200 microliters
- Utilize disposable lab cards to prevent sample crossover and contain biohazardous waste
- Conserve reagents / minimize labor
- Provide reproducible extractions at any concentration of analyte
In controlled studies, Micronics' microFlowª System was used to extract antibiotics across their full physiologic concentration range directly from 80 microliters of whole blood in 4 minutes for subsequent HPLC analysis. Blood cells and protein matter were left behind in waste. Other whole blood applications have shown the extraction of endogenous compounds, such as catecholamines, for the same purpose and in the same timeframe.
