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MesoSystems BioCapture 650
Develop system designs for the BioCapture 650 that meet rigorous biocompatibility, contamination isolation, and cleanability requirements as well as a disposable cartridge that meets collection functional performance goals and optimizes consumable strategy.
The Bioengineering effort closely collaborated with the other Stratos teams as well as Meso's Research and Development team to carefully consider biochemical compatibility of selected materials, processes, and procured OEM components. Main enclosure materials included plastics and elastomers with properties or surface treatments and textures that would be resistant to contaminate trapping and withstand chemicals for decontamination while maintaining cosmetic quality over use. Disposable cartridge materials needed to withstand irradiation and protect sterile fluids while stored.
The disposable fluidic and collection systems also required tight collaboration between Meso and Stratos to effectively make product performance trade-offs while maximizing the integrity of the proprietary collection methodology. Consideration for seal and vent adhesive interaction with sample collection efficiencies and reagent contamination was closely evaluated. Fluid actuation designs were limited to techniques that preserved viable biological samples collected by air sampler.
The resulting designs maximized collection efficiencies, decreased potential contamination or damage to samples, and ensured designs that best meet decontamination and disposable requirements.